亚洲中字幕最新2021芒果

亚洲中字幕最新2021芒果:导师简介-张文

亚洲中字幕最新2021芒果:

发布者:亚洲中字幕最新2021芒果 发布时间:2016-11-03 浏览次数:

导师简介

张文,同济大学教授、博士生导师,上:Q笠┪锕こ碳际跹芯恐行闹魅,兼任中国药学会海洋药物专业委员会副主任委员、上海市海洋湖沼学会副理事长,国内外多种专业杂志的编委及多种SCI杂志的特约审稿人。致力于海洋天然药物先导化合物的发现及关键技术研究。获得国家自然科学基金项目、科技部“863”项目、上海市优秀学科带头人计划、山东省泰山学者领军人才计划等多项基金支持,研究成果发表SCI论文70余篇,获授权专利18项,形成在研新药3项,获上海市药学科技一等奖及国家海洋局海洋科学技术一等奖各1项。应邀撰写上海海洋药物学科发展报告,主编研究生教材《海洋药物导论》。着力推动海洋药物研究关键技术创新与推广,获批上:Q笠┪锕こ碳际跹芯恐行。

近期基金:

1. 自然基金重点国际合作项目:海洋来源新型肿瘤免疫治疗活性小分子的发现及作用靶标研究,2019-2023(主持)

2. 自然基金面上项目:海洋无脊椎动物及共附生菌中抗肿瘤干细胞活性物质的发现及靶点研究,2016-2019(主持)

3. 自然基金地区联合重点项目:东沙珊瑚共生微生物中药用活性菌株的筛选及相关功能基因研究,2015-2018(主持)

4. 上海市优秀学科带头人计划,2015-2018(主持)

5. 泰山学者蓝色领军人才团队支撑计划,2016-2019(主持)

近期论文:

1. H.-L. Wang,# R. Li,# J. Li,# J. He, Z.-Y. Cao, T. Kurtán, A. Mándi, G.-L. Zheng,* W. Zhang.* Alternarin A, a drimane meroterpenoid suppresses neuronal excitability from the coral-associated fungi Alternaria sp. ZH-15. Org. Lett. 2020, 22, 2995-2998.

2. D.-H. Liu,# Y.-Z. Sun,# T. Kurtán, A. Mándi, H. Tang, J. Li, L. Su, C.-L. Zhuang, Z.-Y. Liu,* W. Zhang.* Osteoclastogenesis regulate metabolites from the coral-associated fungus Pseudallescheria boydii TW-1024-3. J. Nat. Prod. 2019, 82, 1274-1282.

3. P. Sun,# F.-Y. Cai,# G. Lauro,# H. Tang, L. Su, H.-L. Wang, H.-H. Li, A. Mándi, T. Kurta?n, R. Riccio, G. Bifulco,* W. Zhang.* Immunomodulatory biscembranoids and assignment of their relative and absolute configurations: data set modulation in the density functional theory/nuclear magnetic resonance approach. J. Nat. Prod. 2019, 82, 1264-1273.

4. J. Li, # H. Tang, # T. Kurtán, A. Mándi, C.-L. Zhuang, L. Su, G.-L. Zheng,* W. Zhang.* Swinhoeisterols from the South China Sea sponge Theonella swinhoei. J. Nat. Prod. 2018, 81, 1645-1650.

5. Y.-Z. Sun, T. Kurtán, A. Mándi, H. Tang, Y. Chou, K. Soong, L. Su, P. Sun, C.-L. Zhuang, W. Zhang.* Immunomodulatory polyketides from a Phoma-like fungus isolated from a soft coral. J. Nat. Prod. 2017, 80, 2930–2940.

6. P. Sun,# Q. Yu,# J. Li, R. Riccio, G. Lauro, G. Bifulco, T. Kurtán, A. Mándi, H. Tang, T.-J. Li, C.-L. Zhuang, W. H. Gerwick, W. Zhang.* Bissubvilides A and B, cembrane-capnosane heterodimers from the soft coral Sarcophyton subviride. J. Nat. Prod. 2016, 79, 2552–2558.

7. J. Gong, P. Sun, N. Jiang, R. Riccio, G. Lauro, G. Bifulco, T.-J. Li, W. H. Gerwick, W. Zhang.* New steroids with a rearranged skeleton as (h)P300 Inhibitors from the sponge Theonella swinhoei. Org Lett 2014, 16, 2224–2227.

8. D.-X. Xu, P. Sun, T. Kurtán, A. Mándi, H. Tang, B.-S. Liu, W. H. Gerwick, Z.-W. Wang,* W. Zhang.* Polyhydroxy cyclohexanols from a Dendrodochium sp. fungus associated with the sea cucumber Holothuria nobilis Selenka. J. Nat. Prod. 2014, 77, 1179-1184.

9. M. Jiang, P. Sun, H. Tang, B.-S. Liu, T.-J. Li, C. Li, W. Zhang.* Steroids glycosylated with both D- and L-arabinoses from the South China Sea gorgonian Dichotella gemmacea. J. Nat. Prod. 2013, 76, 764-768.

10. P. Sun, D.-X. Xu, A. Mándi, T. Kurta?n, T.-J. Li, B. Schulz, W. Zhang.* Structure, absolute configuration, and conformational study of 12-membered macrolides from the fungus Dendrodochium sp. associated with sea cucumber Holothuria nobilis Selenka. J. Org. Chem. 2013, 78, 7030-7047.


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